pentobarbital decreases amounts of toremifene by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. CYP3A4 inducers raise fee of toremifene metabolism, reducing the steady-point out concentration in serum.pentobarbital will lessen the extent or effect of tinidazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. U… Read More